Within our current model of physics it seems highly unlikely. We can determine very specifically how much energy is contained within a particle. The term "electron volt" usually used with the prefix 'giga' or 'tera' reffers to the exact amount of energy that makes up a given particle. The LHC in geneva switzerland works by manipulating these precisely known energies via special relativity.
A parallel idea that is far more feasible is one in which the inside of a black hole contains it's own universe. However even from the outside we can calculate the total energy by determining the black holes mass. Once that is known we can then determine the energy by using e=mc^2.