USP may refer to:
* Heckler & Koch USP pistol.
* NUS University Scholars Programme
* Ultraspiracle protein, a part of the ecdysone receptor
* Unique selling proposition
* Unité Spéciale de la Police, a special unit of the Luxembourg Grand Ducal Police
* United States patent
* United States Pharmacopeia, an official public standards-setting authority for all prescription and over-the-counter medicines and other health care products manufactured or sold in the United States
o USP DI (United States Pharmacopeia Dispensing Information), a comprehensive drug information database that is available online through EBSCO Publishing as well as in two print editions:
+ USP DI Volume I: Drug Information for the Health Care Professional
+ USP DI Volume II: Advice for the Patient, Drug Information in Lay Language
o United States Pharmacopeia unit (USP unit), a standard dosage unit for a drug or vitamin concerning which the United States Food and Drug Administration has determined biological effectiveness; is equal to the international unit in most cases[1]
* Ultrashort pulse laser
* Universal Storage Platform
* University of São Paulo
* University of the Sciences in Philadelphia
* University of the South Pacific
* U.S. Penitentiary
* USp(2n), the symplectic group
* USS Saint Paul
* Utah State Prison
* Uttama Seva Padakkama, a military decoration in Sri Lanka
-- Anyways, would be cool, thought as Dan said, lots of programming and such.